Toxicological Profile for Chromium
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منابع مشابه
Effect of Chromium Supplementation on Blood Glucose, Hemoglobin A1c, Lipid Profile and Lipid Peroxidation in Type 2 Diabetic Patients
Objective: Type 2 diabetes mellitus is a complex metabolic disorder with adverse cardiovascular risk. Chromium (Cr) is an essential nutrient and its role in carbohydrate and lipid metabolism has not been clarified especially in Iran. The aim of this study was to evaluate the effect of chromium picolinate administration on blood glucose, HbA1c, lipid profile and lipid peroxidation in type 2 diab...
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Objective: This study was conducted to assess the toxicity profile of the aqueous-fermented extract of Musa paradisiaca in rats. Materials and Methods: In acute toxicity test, the rats of different groups were orally administered with a single dose of 500, 1000, 2000 and 5000 mg/kg of fermented extract of M. paradisiaca. The rats were monitored for behavioral changes, toxicity signs and mortali...
متن کاملHeme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts.
Several adverse health effects, including irritant and allergic contact dermatitis, have been reported among workers who are occupationally exposed to chromium-containing compounds. Human dermal fibroblasts were used as an in vitro experimental model to study the potential mechanisms underlying hexavalent chromium [Cr(VI)]-induced dermal toxicity. Exposure of the fibroblasts to 5 microM Cr(VI) ...
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Objective: This study aimed at evaluating the bioactive constituents and the toxicological profile of the aqueous fermented seed extract of P. macrophylla. Material and Methods: The chemical constituents of fermented P. macrophylla were assessed using GC-MS. For acute toxicity study, one-time doses of up to 5000 mg/kg of the extract were...
متن کاملValidation of a rat seminiferous tubule culture model as a suitable system for studying toxicant impact on meiosis effect of hexavalent chromium.
There is evidence that exposure to environmental factors is at least partly responsible for changes in semen quality observed over the past decades. The detection of reproductive toxicants under Registration, Evaluation and Authorisation of Chemicals (REACH) will impact animal use for regulatory safety testing. We first validated a model of culture of rat seminiferous tubules for toxicological ...
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تاریخ انتشار 2012